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Protein in Wheat Could Exacerbate Chronic Health Conditions

October 18, 2016

Multiple Sclerosis and other chronic health conditions could be inflamed by a type of protein found in wheat. Amylase-trypsin inhibitors (ATIs) can not only worsen a number of illnesses, but also lead to the inflammation of the bowel and other tissues in the body according to researchers.

Much has been made about gluten being detrimental to MS patients, but this is the first study that has raised the question of grains being harmful.

Despite only making up four per cent of the proteins found in wheat, the consumption of ATIs can have significant effects on the human body such as the inflammation of the gut. As we know inflammation of the gut is a potential trigger for MS symptoms. In addition to inflaming the gut, the research found ATIs can also affect other areas of the body including the lymph nodes, kidneys, spleen and brain.

Lead researcher, Professor Detlef Schuppan, said: “As well as contributing to the development of bowel-related inflammatory conditions, we believe that ATIs can promote inflammation of other immune-related chronic conditions outside of the bowel.”

The researchers also hope the findings will improve knowledge of non-coeliac gluten sensitivity, the condition ascribed to people who benefit from a gluten free diet but do not have coeliac disease.